FALDO: a semantic standard for describing the location of nucleotide and protein feature annotation.

ABSTRACT:

Background

Nucleotide and protein sequence feature annotations are essential to understand biology on the genomic, transcriptomic, and proteomic level. Using Semantic Web technologies to query biological annotations, there was no standard that described this potentially complex location information as subject-predicate-object triples.

Description

We have developed an ontology, the Feature Annotation Location Description Ontology (FALDO), to describe the positions of annotated features on linear and circular sequences. FALDO can be used to describe nucleotide features in sequence records, protein annotations, and glycan binding sites, among other features in coordinate systems of the aforementioned "omics" areas. Using the same data format to represent sequence positions that

SUBMITTER: Bolleman JT 

PROVIDER: S-EPMC4907002 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature