Patient-reported functioning in major depressive disorder.

ABSTRACT:

Objectives

Compared with the general population, patients with major depressive disorder (MDD) report substantial deficits in their functioning that often go beyond the clinical resolution of depressive symptoms. This study examines the impact of MDD and its treatment on functioning.

Methods

From the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial, we analyzed complete data of 2280 adult outpatients with MDD at entry and exit points of each level of antidepressant treatment and again 12 months post treatment. Functioning was measured using the Work and Social Adjustment Scale (WSAS).

Results

The results show that only 7% of patients with MDD reported within-normal functioning before treatment. The proportion of patients achieving within-normal fu

SUBMITTER: IsHak WW 

PROVIDER: S-EPMC4907070 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature