Serum polybrominated diphenyl ether concentrations and thyroid function in young children.

ABSTRACT: Thyroid hormones are essential for proper neurodevelopment in early life. There is evidence that exposure to polybrominated diphenyl ethers (PBDEs) affects thyroid function, but previous studies have been inconsistent, and no studies among children have been conducted in the United States where PBDE levels are particularly high. Serum levels of seven PBDE congeners and thyroid hormones and other thyroid parameters were measured in 80 children aged 1-5 years from the southeastern United States between 2011 and 2012. Parents of the children completed questionnaires with details on demographics and behaviors. Multivariate linear regression models were used to estimate the associations between serum PBDE levels, expressed as quartiles and as log-transformed continuous variables, and markers of

SUBMITTER: Jacobson MH 

PROVIDER: S-EPMC4907865 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature