VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.

ABSTRACT: In healthy individuals, behavioral outcomes are highly associated with the variability on brain regional structure or neurochemical phenotypes. Similarly, in the context of neurodegenerative conditions, neuroimaging reveals that cognitive decline is linked to the magnitude of atrophy, neurochemical declines, or concentrations of abnormal protein aggregates across brain regions. However, modeling the effects of multiple regional abnormalities as determinants of cognitive decline at the voxel level remains largely unexplored by multimodal imaging research, given the high computational cost of estimating regression models for every single voxel from various imaging modalities. VoxelStats is a voxel-wise computational framework to overcome these computational limitations and to perform statist

SUBMITTER: Mathotaarachchi S 

PROVIDER: S-EPMC4908129 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature