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Interaction of BODIPY dyes with bovine serum albumin: a case study on the aggregation of a click-BODIPY dye.


ABSTRACT: The fluorescence of BODIPY and click-BODIPY dyes was found to substantially increase in the presence of bovine serum albumin (BSA). BSA acted as a solubilizer for dye aggregates, in addition to being a conventional binding scaffold for the click-BODIPY dyes, indicating that disaggregation of fluorophores should be considered when evaluating dye-protein interactions.

SUBMITTER: Jameson LP 

PROVIDER: S-EPMC4908817 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature