Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation.

ABSTRACT:

Background

In a randomized trial comparing mitral-valve repair with mitral-valve replacement in patients with severe ischemic mitral regurgitation, we found no significant difference in the left ventricular end-systolic volume index (LVESVI), survival, or adverse events at 1 year after surgery. However, patients in the repair group had significantly more recurrences of moderate or severe mitral regurgitation. We now report the 2-year outcomes of this trial.

Methods

We randomly assigned 251 patients to mitral-valve repair or replacement. Patients were followed for 2 years, and clinical and echocardiographic outcomes were assessed.

Results

Among surviving patients, the mean (±SD) 2-year LVESVI was 52.6±27.7 ml per square meter of body-surface area with mitral-valve repa

SUBMITTER: Goldstein D 

PROVIDER: S-EPMC4908819 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature