Characterizing Long-Term Health Related Quality of Life Trajectories of Individuals With Opioid Use Disorder.

ABSTRACT:

Objectives

Health related quality of life (HRQoL) has been increasingly considered an endpoint in evaluations of treatment for substance use disorders. We aimed to characterize longitudinal patterns of HRQoL in individuals with opioid use disorder (OUD) and with a history of opioid agonist treatment (OAT) with methadone.

Methods

The EuroQol EQ-5D, a preference-weighted measure of HRQoL, was assessed in individuals with OUD and with a history of OAT enrolled in three prospective cohort studies between December 2011 and May 2014, with a maximum of five biannual assessments. We used latent class growth analysis to identify HRQoL trajectory classes and their association with self-reported current OAT receipt. Class assignment was derived from posterior probabilities and we explo

SUBMITTER: Krebs E 

PROVIDER: S-EPMC4908824 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature