Comparison of risk scores for the prediction of stroke in African Americans: Findings from the Jackson Heart Study.

ABSTRACT:

Background

Evidence from existing cohort studies supports the prediction of incident coronary heart disease and stroke using 10-year cardiovascular disease (CVD) risk scores and the American Heart Association/American Stroke Association's cardiovascular health (CVH) metric.

Methods

We included all Jackson Heart Study participants with complete scoring information at the baseline study visit (2000-2004) who had no history of stroke (n = 4,140). We used Kaplan-Meier methods to calculate the cumulative incidence of stroke and used Cox models to estimate hazard ratios and 95% CIs for stroke according to CVD risk and CVH score. We compared the discrimination of the 2 models according to the Harrell c index and plotted predicted vs observed stroke risk calibration plots for each o

SUBMITTER: Foraker RE 

PROVIDER: S-EPMC4908834 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature