Parallel Evolution of Copy-Number Variation across Continents in Drosophila melanogaster.

ABSTRACT: Genetic differentiation across populations that is maintained in the presence of gene flow is a hallmark of spatially varying selection. In Drosophila melanogaster, the latitudinal clines across the eastern coasts of Australia and North America appear to be examples of this type of selection, with recent studies showing that a substantial portion of the D. melanogaster genome exhibits allele frequency differentiation with respect to latitude on both continents. As of yet there has been no genome-wide examination of differentiated copy-number variants (CNVs) in these geographic regions, despite their potential importance for phenotypic variation in Drosophila and other taxa. Here, we present an analysis of geographic variation in CNVs in D. melanogaster. We also present the first genomic an

SUBMITTER: Schrider DR 

PROVIDER: S-EPMC4909135 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature