Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study.

ABSTRACT:

Objectives

Organophosphates (OPs) are among the most commonly used insecticides. OPs have been linked to cancer risk in some epidemiological studies, which have been largely conducted in predominantly male populations. We evaluated personal use of specific OPs and cancer incidence among female spouses of pesticide applicators in the prospective Agricultural Health Study cohort.

Methods

At enrolment (1993-1997), spouses provided information about ever use of specific pesticides, including 10 OPs, demographic information, reproductive health history and other potential confounders. We used Poisson regression to estimate relative risks (RRs) and 95% CIs for all cancers diagnosed through 2010 for North Carolina and through 2011 for Iowa.

Results

Among 30,003 women, 25.9%

SUBMITTER: Lerro CC 

PROVIDER: S-EPMC4909328 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature