Enrollment Yield and Reasons for Screen Failure in a Large Prehospital Stroke Trial.

ABSTRACT:

Background and purpose

The enrollment yield and reasons for screen failure in prehospital stroke trials have not been well delineated.

Methods

The Field Administration of Stroke Therapy-Magnesium (FAST-MAG) trial identified patients for enrollment using a 2 stage screening process-paramedics in person followed by physician-investigators by cell phone. Outcomes of consecutive screening calls from paramedics to enrolling physician-investigators were prospectively recorded.

Results

From 2005 to 2012, 4458 phone calls were made by paramedics to physician-investigators, an average of 1 call per vehicle every 135.7 days. A total of 1700 (38.1%) calls resulted in enrollments. The rate of enrollment of stroke mimics was 3.9%. Among the 2758 patients not enrolled, 3140 reasons

SUBMITTER: Kim DH 

PROVIDER: S-EPMC4909489 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature