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Fixed cutaneous sporotrichosis treated with topical amphotericin B in an immune suppressed patient.

ABSTRACT: Both fixed cutaneous and lymphocutaneous sporotrichosis are associated with significant morbidity due to chronicity. Although treatment with itraconazole, saturated solution of potassium iodide or terbinafine is recommended in most cases, the described patient with fixed cutaneous sporotrichosis could not tolerate any of these. Her lesion healed after 8weeks of topical amphotericin-B (0.1% w/w). Topical amphotericin-B appears useful treatment modality for uncomplicated cutaneous sporotrichosis when systemic treatment needs deferment, remains contraindicated, or in pediatric patients.

SUBMITTER: Mahajan VK

PROVIDER: S-EPMC4909862 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Fixed cutaneous sporotrichosis treated with topical amphotericin B in an immune suppressed patient.

Mahajan Vikram K VK Mehta Karaninder S KS Chauhan Pushpinder S PS Gupta Mrinal M Sharma Rajni R Rawat Ritu R

Medical mycology case reports 20150124

Both fixed cutaneous and lymphocutaneous sporotrichosis are associated with significant morbidity due to chronicity. Although treatment with itraconazole, saturated solution of potassium iodide or terbinafine is recommended in most cases, the described patient with fixed cutaneous sporotrichosis could not tolerate any of these. Her lesion healed after 8weeks of topical amphotericin-B (0.1% w/w). Topical amphotericin-B appears useful treatment modality for uncomplicated cutaneous sporotrichosis w ...[more]

PMID: 27330943

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