Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum.

ABSTRACT: Eukaryotic cells repress global translation and selectively upregulate stress response proteins by altering multiple steps in gene expression. In this study, genome-wide transcriptome analysis of cellular adaptation to thermal stress was performed on the plant pathogenic fungus Fusarium graminearum. The results revealed that profound alterations in gene expression were required for heat shock responses in F. graminearum. Among these proteins, heat shock protein 90 (FgHsp90) was revealed to play a central role in heat shock stress responses in this fungus. FgHsp90 was highly expressed and exclusively localised to nuclei in response to heat stress. Moreover, our comprehensive functional characterisation of FgHsp90 provides clear genetic evidence supporting its crucial roles in the vegetative

SUBMITTER: Bui DC 

PROVIDER: S-EPMC4910114 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature