Whole Grain Intake and Mortality From All Causes, Cardiovascular Disease, and Cancer: A Meta-Analysis of Prospective Cohort Studies.

ABSTRACT:

Background

Current findings on associations between whole grain (WG) intake and mortality are inconsistent and have not been summarized by meta-analysis.

Methods and results

We searched for prospective cohort studies reporting associations between WG intake and mortality from all causes, cardiovascular disease (CVD), and cancer through February 2016 in Medline, Embase, and clinicaltrials.gov, and we further included unpublished results from National Health and Nutrition Examination Survey (NHANES) III and NHANES 1999 to 2004. Fourteen studies were eligible for analysis, which included 786 076 participants, 97 867 total deaths, 23 957 CVD deaths, and 37 492 cancer deaths. Pooled relative risks comparing extreme WG categories (high versus low) were 0.84 (95% confidence interva

SUBMITTER: Zong G 

PROVIDER: S-EPMC4910651 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature