Ontology highlight
ABSTRACT:
SUBMITTER: Kim J
PROVIDER: S-EPMC4910761 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Investigative and clinical urology 20160526
Bladder cancer remains the most immunogenic and expensive malignant tumor in the United States today. As the 4th leading cause of death from cancer in United States, Immunotherapy blocking immune checkpoints have been recently been applied to many aggressive cancers and changed interventions of urological cancers including advanced bladder cancer. The applied inhibition of PD-1-PD-L1 interactions can restore antitumor T-cell activity and enhance the cellular immune attack on antigens. The overal ...[more]