A simple rapid process for semi-automated brain extraction from magnetic resonance images of the whole mouse head.

ABSTRACT:

Background

Magnetic resonance imaging (MRI) is a well-developed technique in neuroscience. Limitations in applying MRI to rodent models of neuropsychiatric disorders include the large number of animals required to achieve statistical significance, and the paucity of automation tools for the critical early step in processing, brain extraction, which prepares brain images for alignment and voxel-wise statistics.

New method

This novel timesaving automation of template-based brain extraction ("skull-stripping") is capable of quickly and reliably extracting the brain from large numbers of whole head images in a single step. The method is simple to install and requires minimal user interaction.

Results

This method is equally applicable to different types of MR images. Resul

SUBMITTER: Delora A 

PROVIDER: S-EPMC4910826 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature