CADASIL: Migraine, Encephalopathy, Stroke and Their Inter-Relationships.

ABSTRACT:

Background

Migraine is common in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) but its treatment responses are not well described, and its relationship to stroke risk unknown. Encephalopathy is a less common presentation; it has been suggested it is related to migraine. We characterised migraine patterns and treatment responses in CADASIL, and examined associations between migraine and both stroke risk and encephalopathy.

Methods

300 symptomatic CADASIL patients were prospectively recruited from a national referral clinic over a nineteen year period, from 1996 to 2015. Data was collected using a standardised questionnaire. Migraine was classified according to the International Classification of Headache Disorders, 3rd ed

SUBMITTER: Tan RY 

PROVIDER: S-EPMC4911105 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature