Alcohol consumption and colon cancer prognosis among participants in north central cancer treatment group phase III trial N0147.

ABSTRACT: Alcohol consumption is associated with a modest increased risk of colon cancer, but its relationship with colon cancer survival has not been elucidated. Using data from a phase III randomized adjuvant trial, we assessed the association of alcohol consumption with colon cancer outcomes. Patients completed a risk factor questionnaire before randomization to FOLFOX or FOLFOX + cetuximab (N = 1984). Information was collected on lifestyle factors, including smoking, physical activity and consumption of different types of alcohol. Cox models assessed the association between alcohol consumption and outcomes of disease-free survival (DFS), time-to-recurrence (TTR) and overall survival (OS), adjusting for age, sex, study arm, body mass, smoking, physical activity and performance status. No statisti

SUBMITTER: Phipps AI 

PROVIDER: S-EPMC4911257 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature