An Empiric HIV Risk Scoring Tool to Predict HIV-1 Acquisition in African Women.

ABSTRACT:

Objective

To develop and validate an HIV risk assessment tool to predict HIV acquisition among African women.

Design

Data were analyzed from 3 randomized trials of biomedical HIV prevention interventions among African women (VOICE, HPTN 035, and FEM-PrEP).

Methods

We implemented standard methods for the development of clinical prediction rules to generate a risk-scoring tool to predict HIV acquisition over the course of 1 year. Performance of the score was assessed through internal and external validations.

Results

The final risk score resulting from multivariable modeling included age, married/living with a partner, partner provides financial or material support, partner has other partners, alcohol use, detection of a curable sexually transmitted infection, an

SUBMITTER: Balkus JE 

PROVIDER: S-EPMC4911322 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature