Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease.

ABSTRACT:

Background

L-carnitine (LC) plays an important physiologic role in lipid metabolism. To date, no clinical study has been performed to examine the effect of LC supplementation on the lipid status of coronary artery disease (CAD) patients. The aim of this study was to investigate the lipid lowering effects of LC supplementation (1000 mg/d) in CAD patients.

Methods

CAD patients were identified by cardiac catheterization as having at least 50 % stenosis of one major coronary artery. Forty-seven subjects were recruited and randomly assigned to the placebo (n = 24) and to the LC (n = 23) groups. The intervention was administered for 12 weeks. The levels of LC, lipid profiles, and antioxidant enzyme activity (superoxide dismutase, SOD) were measured.

Results

The subjects in

SUBMITTER: Lee BJ 

PROVIDER: S-EPMC4912751 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature