Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.
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ABSTRACT:
SUBMITTER: NINDS Stroke Genetics Network (SiGN)
PROVIDER: S-EPMC4912948 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.
The Lancet. Neurology 20151219 2
<h4>Background</h4>The discovery of disease-associated loci through genome-wide association studies (GWAS) is the leading genetic approach to the identification of novel biological pathways underlying diseases in humans. Until recently, GWAS in ischaemic stroke have been limited by small sample sizes and have yielded few loci associated with ischaemic stroke. We did a large-scale GWAS to identify additional susceptibility genes for stroke and its subtypes.<h4>Methods</h4>To identify genetic loci ...[more]
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