Neuromusculoskeletal Model Calibration Significantly Affects Predicted Knee Contact Forces for Walking.

ABSTRACT: Though walking impairments are prevalent in society, clinical treatments are often ineffective at restoring lost function. For this reason, researchers have begun to explore the use of patient-specific computational walking models to develop more effective treatments. However, the accuracy with which models can predict internal body forces in muscles and across joints depends on how well relevant model parameter values can be calibrated for the patient. This study investigated how knowledge of internal knee contact forces affects calibration of neuromusculoskeletal model parameter values and subsequent prediction of internal knee contact and leg muscle forces during walking. Model calibration was performed using a novel two-level optimization procedure applied to six normal walking trials

SUBMITTER: Serrancoli G 

PROVIDER: S-EPMC4913205 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature