Predictors of Sudden Cardiac Death in Doberman Pinschers with Dilated Cardiomyopathy.

ABSTRACT:

Background

Doberman Pinschers with dilated cardiomyopathy (DCM) are at high risk of sudden cardiac death (SCD). Risk factors for SCD are poorly defined.

Aim

To assess cardiac biomarkers, Holter-ECG, echocardiographic variables and canine characteristics in a group of Doberman Pinschers with DCM dying of SCD and in a DCM control group to identify factors predicting SCD.

Methods/animals

A longitudinal prospective study was performed in 95 Doberman Pinschers with DCM. Forty-one dogs died within 3 months after the last cardiac examination (SCD-group) and were compared to 54 Doberman Pinschers with DCM surviving 1 year after inclusion. Holter-ECG, echocardiography, measurement of N-terminal prohormone of brain-natriuretic peptide (NT-proBNP), and cardiac Troponin I (cTnI)

SUBMITTER: Kluser L 

PROVIDER: S-EPMC4913570 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature