Treatment of Disseminated Aspergillosis with Posaconazole in 10 Dogs.

ABSTRACT:

Background

Few effective treatments for disseminated Aspergillus infections in dogs are available. Posaconazole has potent and broad-spectrum activity against Aspergillus spp., but its use has not yet been sufficiently evaluated in dogs.

Hypothesis/objectives

The aim of this study was to determine the safety and efficacy of posaconazole for the treatment of naturally occurring disseminated Aspergillus infections in dogs.

Animals

Ten client-owned dogs with disseminated aspergillosis.

Methods

Prospective, nonrandomized, noncontrolled study with posaconazole administered to dogs at dosage of 5 mg/kg p.o. q12h. The primary veterinarian or the veterinary specialist caring for the dogs provided patient data.

Results

The treatment response for dogs with dissemi

SUBMITTER: Corrigan VK 

PROVIDER: S-EPMC4913654 | biostudies-literature | 2016 Jan-Feb

REPOSITORIES: biostudies-literature