Atypically rightward cerebral asymmetry in male adults with autism stratifies individuals with and without language delay.

ABSTRACT: In humans, both language and fine motor skills are associated with left-hemisphere specialization, whereas visuospatial skills are associated with right-hemisphere specialization. Individuals with autism spectrum conditions (ASC) show a profile of deficits and strengths that involves these lateralized cognitive functions. Here we test the hypothesis that regions implicated in these functions are atypically rightward lateralized in individuals with ASC and, that such atypicality is associated with functional performance. Participants included 67 male, right-handed adults with ASC and 69 age- and IQ-matched neurotypical males. We assessed group differences in structural asymmetries in cortical regions of interest with voxel-based analysis of grey matter volumes, followed by correlational ana

SUBMITTER: Floris DL 

PROVIDER: S-EPMC4913747 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature