Fatty acid-releasing activities in Sinorhizobium meliloti include unusual diacylglycerol lipase.

ABSTRACT: Phospholipids are well known for their membrane-forming properties and thereby delimit any cell from the exterior world. In addition, membrane phospholipids can act as precursors for signals and other biomolecules during their turnover. Little is known about phospholipid signalling, turnover and remodelling in bacteria. Recently, we showed that a FadD-deficient mutant of Sinorhizobium meliloti, unable to convert free fatty acids to their coenzyme A derivatives, accumulates free fatty acids during the stationary phase of growth. Enzymatic activities responsible for the generation of these free fatty acids were unknown in rhizobia. Searching the genome of S. meliloti, we identified a potential lysophospholipase (SMc04041) and two predicted patatin-like phospholipases A (SMc00930, SMc01003).

SUBMITTER: Sahonero-Canavesi DX 

PROVIDER: S-EPMC4914366 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature