Lifetime occupational and leisure time physical activity and risk of Parkinson's disease.

ABSTRACT:

Introduction

While regular exercise has been shown to alleviate the motor symptoms of Parkinson's disease (PD), it remains unclear whether a physically active lifestyle may prevent PD.

Methods

To examine physical activities across the lifespan and risk of PD, we relied on data from a population-based case-control study that enrolled 357 incident PD cases and 341 controls. We assessed physical activity levels via self-report of (1) overall physical activity (PA) over 4 age periods; (2) competitive sports; and (3) occupational histories.

Results

PD risks were lower comparing the overall PA highest quartile (moderate to vigorous activities ≥180 metabolic equivalent task-hours/week (MET-h/wk)) with the lowest quartile (<47.8 MET-h/wk) in age-period 18-24 years (adjusted o

SUBMITTER: Shih IF 

PROVIDER: S-EPMC4914446 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature