Management of nodal recurrences of endometrial cancer with IMRT.

ABSTRACT:

Objective

Pelvic and paraortic lymph nodal regions are frequent sites of relapse in women with endometrial cancer who have not undergone adjuvant external beam radiation. We investigated outcomes after definitive management of nodal relapses of endometrial cancer with intensity modulated radiation therapy (IMRT).

Methods

Between 2002-2012, 38 patients with endometrial cancer who had no prior external beam radiation were treated definitively using IMRT for regionally confined pelvic or paraortic nodal recurrences. Thirteen (34%) had chemotherapy prior to radiation, and 21 (55%) received concurrent chemotherapy. The nodal basins were typically treated to 45-50Gy, with a boost to the gross tumor to a median total of 64.7Gy (range 59-73Gy).

Results

The median overall surv

SUBMITTER: Ho JC 

PROVIDER: S-EPMC4915591 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature