Analysis of Clinical Factors Associated with Retinal Morphological Changes in Patients with Primary Sjogren's Syndrome.

ABSTRACT:

Purpose

To investigate clinical factors associated with abnormal retinal morphologies in patients with primary Sjögren's syndrome (pSS).

Methods

One-hundred-thirty patients with pSS who underwent immunoserological tests, minor salivary gland biopsies, and optical coherence tomography examinations were retrospectively analyzed. Risk factors for abnormally reduced peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell-inner plexiform layer (mGCIPL) thicknesses were evaluated, as well as the correlation between clinical factors and pRNFL and mGCIPL thicknesses.

Results

Anti-Sjögren's syndrome type B (SSB) antibody positivity (P = 0.048) was identified as a risk factor associated with abnormally reduced pRNFL thickness, and anti-SSB positivity (P = 0.00

SUBMITTER: Yang JM 

PROVIDER: S-EPMC4915668 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature