Is selective prenatal iron prophylaxis better than routine prophylaxis: final results of a trial (PROFEG) in Maputo, Mozambique.

ABSTRACT:

Objective

To compare routine versus selective (ie, screening and treatment for anaemia) prenatal iron prophylaxis in a malaria-endemic and HIV-prevalent setting, an extended analysis including previously missing data.

Design

A pragmatic randomised controlled clinical trial.

Setting

2 health centres in Maputo, Mozambique.

Participants

Pregnant women (≥18 years old; non-high-risk pregnancy) were randomly allocated to routine iron (n=2184) and selective iron (n=2142) groups.

Interventions

In the routine group, women received 60 mg ferrous sulfate plus 400 μg folic acid daily. In the selective group, women received 1 mg of folic acid daily and haemoglobin (Hb) screening at each visit; with low Hb (cut-off 9 g/dL) treatment (120 mg+800 μg of folic acid daily)

SUBMITTER: Hemminki E 

PROVIDER: S-EPMC4916582 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature