A Diagnostic Scoring Model for Leptospirosis in Resource Limited Settings.

ABSTRACT:

Background

Leptospirosis is a zoonotic infection with significant morbidity and mortality. The clinical presentation of leptospirosis is known to mimic the clinical profile of other prevalent tropical fevers. Laboratory confirmation of leptospirosis is based on the reference standard microscopic agglutination test (MAT), direct demonstration of the organism, and isolation by culture and DNA detection by polymerase chain reaction (PCR) amplification. However these methods of confirmation are not widely available in resource limited settings where the infection is prevalent, and reliance is placed on clinical features for provisional diagnosis. In this prospective study, we attempted to develop a model for diagnosis of leptospirosis, based on clinical features and standard laboratory

SUBMITTER: Rajapakse S 

PROVIDER: S-EPMC4917116 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature