Deciphering bifidobacterial-mediated metabolic interactions and their impact on gut microbiota by a multi-omics approach.

ABSTRACT: The intricacies of cooperation and competition between microorganisms are poorly investigated for particular components of the gut microbiota. In order to obtain insights into the manner by which different bifidobacterial species coexist in the mammalian gut, we investigated possible interactions between four human gut commensals, Bifidobacterium bifidum PRL2010, Bifidobacterium adolescentis 22L, Bifidobacterium breve 12L and Bifidobacterium longum subsp. infantis ATCC15697, in the intestine of conventional mice. The generated information revealed various ecological/metabolic strategies, including glycan-harvesting, glycan-breakdown and cross-feeding behavior, adopted by bifidobacteria in the highly competitive environment of the mammalian intestine. Introduction of two or multiple bifidob

SUBMITTER: Turroni F 

PROVIDER: S-EPMC4918443 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature