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Intellectual Disability: When the Hypertrichosis Is a Clue.

ABSTRACT: The skin and the central and peripheral nervous system both derive from the ectoderm ridge. Therefore, several syndromes characterized by the presence of intellectual disability (ID) can be associated with specific congenital cutaneous manifestations. In this review, we list some of the most frequent diseases characterized by the presence of ID associated with hirsutism, which might be an incentive for the clinicians to pay attention to the ectodermal annexes in patients with ID.

SUBMITTER: Pezzani L

PROVIDER: S-EPMC4918720 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

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Intellectual Disability: When the Hypertrichosis Is a Clue.

Pezzani Lidia L Milani Donatella D Tadini Gianluca G

Journal of pediatric genetics 20150928 3

The skin and the central and peripheral nervous system both derive from the ectoderm ridge. Therefore, several syndromes characterized by the presence of intellectual disability (ID) can be associated with specific congenital cutaneous manifestations. In this review, we list some of the most frequent diseases characterized by the presence of ID associated with hirsutism, which might be an incentive for the clinicians to pay attention to the ectodermal annexes in patients with ID. ...[more]

PMID: 27617126

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