The Worsening Profile of Alcoholic Hepatitis in the United States.

ABSTRACT:

Background

Alcoholic hepatitis (AH) is a major cause of liver-related hospitalization. The profile, treatment patterns, and outcomes of subjects admitted for AH in routine clinical practice are unknown. Also, it is not known whether these are changing over time. This study is thus aimed to identify temporal trends in hospitalization rates, clinical characteristics, treatment patterns, and outcomes of subjects admitted for AH in a routine clinical setting.

Methods

A retrospective analysis of adults admitted for AH from 2000 to 2011 was performed using an anonymized EMR database of patient-level data from 169 U.S. medical centers.

Results

(i)

Epidemiology

The proportion of baby boomers admitted for AH increased from 2000 to 2011 (26 to 31%, p < 0.0001). (ii)

C

SUBMITTER: Nguyen TA 

PROVIDER: S-EPMC4918810 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature