The effect of 1 mg folic acid supplementation on clinical outcomes in female migraine with aura patients.

ABSTRACT:

Background

Migraine is a common neurovascular condition that may be linked to hyperhomocysteinemia. We have previously provided evidence that reduction of homocysteine with a vitamin supplementation can reduce the occurrence of migraine in women. The current study examined the occurrence of migraine in response to vitamin supplementation with a lower dose of folic acid.

Methods

This was a 6 month randomised, double blinded placebo controlled trial of daily vitamin supplementation containing 1 mg of folic acid, 25 mg of Vitamin B6 and Vitamin B12, on reduction of homocysteine and the occurrence of migraine in 300 female patients diagnosed with migraine with aura.

Results

Vitamin supplementation with 1 mg of folic acid, did not significantly decrease homocysteine levels

SUBMITTER: Menon S 

PROVIDER: S-EPMC4919187 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature