Vitamin D status of black and white Americans and changes in vitamin D metabolites after varied doses of vitamin D supplementation.

ABSTRACT:

Background

Controversy exists over the disparate circulating 25-hydroxyvitamin D [25(OH)D] concentrations between black and white Americans.

Objective

We sought to determine whether there are differences in total and directly measured free 25(OH)D concentrations between black and white American adults and how daily supplementation with cholecalciferol changes these concentrations.

Design

Cross-sectional and longitudinal analyses were conducted with the use of data from 2 placebo-controlled, randomized trials at 2 academic medical centers in the United States: CaDDM (Calcium and Vitamin D in Type 2 Diabetes) and DDM2 (Vitamin D for Established Type 2 Diabetes). A total of 208 subjects with pre- or well-controlled diabetes with a mean age of 59.1 y and mean body mass in

SUBMITTER: Alzaman NS 

PROVIDER: S-EPMC4919528 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature