Ultra-long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion.

ABSTRACT:

Background

The intake of sodium, chloride, and potassium is considered important to healthy nutrition and cardiovascular disease risk. Estimating the intake of these electrolytes is difficult and usually predicated on urine collections, commonly for 24 h, which are considered the gold standard. We reported on data earlier for sodium but not for potassium or chloride.

Objective

We were able to test the value of 24-h urine collections in a unique, ultra-long-term balance study conducted during a simulated trip to Mars.

Design

Four healthy men were observed while ingesting 12 g salt/d, 9 g salt/d, and 6 g salt/d, while their potassium intake was maintained at 4 g/d for 105 d. Six healthy men were studied while ingesting 12 g salt/d, 9 g salt/d, and 6 g salt/d, with a re-

SUBMITTER: Birukov A 

PROVIDER: S-EPMC4919532 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature