Exploration of Circadian Rhythms in Patients with Bilateral Vestibular Loss.

ABSTRACT:

Background

New insights have expanded the influence of the vestibular system to the regulation of circadian rhythmicity. Indeed, hypergravity or bilateral vestibular loss (BVL) in rodents causes a disruption in their daily rhythmicity for several days. The vestibular system thus influences hypothalamic regulation of circadian rhythms on Earth, which raises the question of whether daily rhythms might be altered due to vestibular pathology in humans. The aim of this study was to evaluate human circadian rhythmicity in people presenting a total bilateral vestibular loss (BVL) in comparison with control participants.

Methodology and principal findings

Nine patients presenting a total idiopathic BVL and 8 healthy participants were compared. Their rest-activity cycle was recorded

SUBMITTER: Martin T 

PROVIDER: S-EPMC4920359 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature