Isolation of Infective Zika Virus from Urine and Saliva of Patients in Brazil.

ABSTRACT:

Background

Zika virus (ZIKV) is an emergent threat provoking a worldwide explosive outbreak. Since January 2015, 41 countries reported autochthonous cases. In Brazil, an increase in Guillain-Barré syndrome and microcephaly cases was linked to ZIKV infections. A recent report describing low experimental transmission efficiency of its main putative vector, Ae. aegypti, in conjunction with apparent sexual transmission notifications, prompted the investigation of other potential sources of viral dissemination. Urine and saliva have been previously established as useful tools in ZIKV diagnosis. Here, we described the presence and isolation of infectious ZIKV particles from saliva and urine of acute phase patients in the Rio de Janeiro state, Brazil.

Methodology/principal findings

SUBMITTER: Bonaldo MC 

PROVIDER: S-EPMC4920388 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature