Neurogenomics in Africa: Perspectives, progress, possibilities and priorities.

ABSTRACT: The understanding of the genetic basis of neurological disorders has grown rapidly in the last two decades. Despite the genomic heterogeneity within African populations, large-scale candidate gene or linkage and exome studies are lacking. However, current knowledge on neurogenetics in African populations is limited and geographically very uneven. Isolated reports indicate the existence of autosomal dominant or recessive conditions incorporating cerebrovascular, movement, neuromuscular, seizure and motor neuron disorders in Africans. In addition, few African families with neurodegenerative disorders associated with dementia have been characterized in North, West and South Africa. The current insurgency in genomic research triggered by among others the Human Health and Heredity (H3) Africa I

SUBMITTER: Akinyemi RO 

PROVIDER: S-EPMC4920548 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature