African Descent and Glaucoma Evaluation Study (ADAGES): Racial Differences in Optic Disc Hemorrhage and Beta-Zone Parapapillary Atrophy.

ABSTRACT:

Purpose

To investigate the differences in the frequency of optic disc hemorrhage (DH) and prevalence of beta-zone parapapillary atrophy (βPPA) between individuals of African descent (AD) and European descent (ED).

Design

Prospective, multicenter, observational cohort.

Participants

A total of 1950 eyes of 1172 participants of the African Descent and Glaucoma Evaluation Study (ADAGES).

Methods

Stereoscopic disc photographs of subjects with and without glaucomatous optic neuropathy (GON) followed during the first 13 years of the ADAGES underwent masked review searching for DH and βPPA. A total of 928 eyes (non-GON, 581; GON, 347) of 551 AD patients (non-GON, 334; GON, 217) and 1022 eyes (non-GON, 568; GON, 454) of 611 ED patients (non-GON, 334; GON, 277) were incl

SUBMITTER: Skaat A 

PROVIDER: S-EPMC4921256 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature