Graph-Theoretical Study of Functional Changes Associated with the Iowa Gambling Task.

ABSTRACT: The primary aim of this study was to examine changes in functional brain network organization from rest to the Iowa Gambling Task (IGT) using a graph-theoretical approach. Although many functional neuroimaging studies have examined task-based activations in complex-decision making tasks, changes in functional network organization during this task remain unexplored. This study used a repeated-measures approach to examine changes in functional network organization across multiple sessions of resting-state and IGT scans. The results revealed that global network organization shifted from a local, clustered organization at rest to a more global, integrated organization during the IGT. In addition, network organization was stable across sessions of rest and the IGT. Regional analyses of the Defa

SUBMITTER: Bolt T 

PROVIDER: S-EPMC4921456 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature