Correlation of primary middle and distal esophageal cancers motion with surrounding tissues using four-dimensional computed tomography.

ABSTRACT:

Purpose

To investigate the correlation of gross tumor volume (GTV) motion with the structure of interest (SOI) motion and volume variation for middle and distal esophageal cancers using four-dimensional computed tomography (4DCT).

Patients and methods

Thirty-three patients with middle or distal esophageal carcinoma underwent 4DCT simulation scan during free breathing. All image sets were registered with 0% phase, and the GTV, apex of diaphragm, lung, and heart were delineated on each phase of the 4DCT data. The position of GTV and SOI was identified in all 4DCT phases, and the volume of lung and heart was also achieved. The phase relationship between the GTV and SOI was estimated through Pearson's correlation test.

Results

The mean peak-to-peak displacement of all pri

SUBMITTER: Wang W 

PROVIDER: S-EPMC4922815 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature