Concise Review: Pancreatic Cancer and Bone Marrow-Derived Stem Cells.

ABSTRACT:

Unlabelled

Pancreatic adenocarcinoma remains one of the most challenging diseases of modern gastroenterology, and, even though considerable effort has been put into understanding its pathogenesis, the exact molecular mechanisms underlying the development and/or systemic progression of this malignancy still remain unclear. Recently, much attention has been paid to the potential role of bone marrow-derived stem cells (BMSCs) in this malignancy. Hence, herein, we comprehensively review the most recent discoveries and current achievements and concepts in this field. Specifically, we discuss the significance of identifying pancreatic cancer stem cells and novel therapeutic approaches involving molecular interference of their metabolism. We also describe advances in the current understan

SUBMITTER: Blogowski W 

PROVIDER: S-EPMC4922853 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature