Hemiablative Focal Low Dose Rate Brachytherapy: A Phase II Trial Protocol.

ABSTRACT:

Background

The objective of focal brachytherapy (BT) is to provide effective prostate cancer control for low-risk disease but with reduced genitourinary, gastrointestinal and sexual side effects in a cost-effective way.

Objective

The aim of this study is to describe a phase II study examining technical and dosimetric feasibility and toxicity, quality of life changes, and local control with post-treatment biopsy outcomes in men with early stage low volume prostate cancer treated with focal iodine-125 seed BT.

Methods

The study design is a prospective, multicenter trial with a planned sample size of 20 patients including men with a minimum age of 60 years, a life expectancy estimated to be greater than 10 years, with low or low-tier intermediate risk prostate cancer, un

SUBMITTER: Fernandez Ots A 

PROVIDER: S-EPMC4923592 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature