Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review.

ABSTRACT: Although intravenous thrombolysis increases the probability of a good functional outcome in carefully selected patients with acute ischemic stroke, a substantial proportion of patients who receive thrombolysis do not have a good outcome. Several recent trials of mechanical thrombectomy appear to indicate that this treatment may be superior to thrombolysis. We therefore conducted a systematic review and meta-analysis to evaluate the clinical effectiveness and safety of new-generation mechanical thrombectomy devices with intravenous thrombolysis (if eligible) compared with intravenous thrombolysis (if eligible) in patients with acute ischemic stroke caused by a proximal intracranial occlusion. We systematically searched seven databases for randomized controlled trials published between Janua

SUBMITTER: Lambrinos A 

PROVIDER: S-EPMC4926268 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature