Ontology highlight
ABSTRACT:
SUBMITTER: Strong BSI
PROVIDER: S-EPMC4926280 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Scientific reports 20160629
Invariant NKT (iNKT) cells are critical to the maintenance of tolerance toward alloantigens encountered during postnatal life pointing to the existence of a process for self-education. However, the impact of developmentally encountered alloantigens in shaping the phenotype and function of iNKT cells has not been described. To better understand this process, the current report examined naïve iNKT cells as they matured in an allogeneic environment. Following the prenatal transfer of fetal hematopo ...[more]