Adverse Cardiovascular Response to Aerobic Exercise Training: Is This a Concern?

ABSTRACT:

Purpose

Aerobic exercise training in sedentary individuals improves physical fitness and various cardiovascular (CV) biomarkers. Nevertheless, there has been controversy as to whether exercise training may adversely affect some biomarkers in a small segment of the population. The purpose of this study was to investigate whether clinically significant worsening of CV biomarkers was more prevalent among individuals randomized to a supervised endurance training program as compared with those randomized to a control condition.

Methods

Baseline and end of study measurements of fasting insulin (FI), triglycerides (TG), resting systolic blood pressure (SBP), and HDL cholesterol (HDL-C) were obtained on 1188 healthy sedentary subjects from 4 clinical studies. Each study randomized s

SUBMITTER: Leifer ES 

PROVIDER: S-EPMC4926311 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature