Association between gastrointestinal events and compliance with osteoporosis therapy.

ABSTRACT:

Purpose

The aim of this study was to estimate the rate of gastrointestinal (GI) events, and association between GI events and compliance with osteoporosis therapy among osteoporotic women.

Methods

A retrospective cohort study using a large administrative claims database in the United States from 2001 through 2010 was conducted. We studied women ≥ 55 years old who were continuously enrolled in a health plan for at least 2 years, a baseline year before and a follow-up year after the date of the first prescription of oral bisphosphonate as the first oral osteoporosis treatment. Compliance with osteoporosis therapy was measured using the medication possession ratio (MPR), with compliance defined as MPR ≥ 0.8. Multivariate logistic regression was used to assess the association be

SUBMITTER: Siris ES 

PROVIDER: S-EPMC4926838 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature