Home testing and counselling to reduce HIV incidence in a generalised epidemic setting: a mathematical modelling analysis.

ABSTRACT:

Background

Home HIV testing and counselling (HTC) achieves high levels of HIV testing and linkage to care. Periodic home HTC, particularly targeted to those with high HIV viral load, might facilitate expansion of antiretroviral therapy (ART) coverage. We used a mathematical model to assess the effect of periodic home HTC programmes on HIV incidence in KwaZulu-Natal, South Africa.

Methods

We developed a dynamic HIV transmission model with parameters, primary cost data, and measures of viral suppression collected from a prospective study of home HTC in KwaZulu-Natal. In our model, we assumed home HTC took place every 5 years with ART initiation for people with CD4 counts of 350 cells per μL or less. For individuals with CD4 counts of more than 350 cells per μL, we compared inc

SUBMITTER: Ying R 

PROVIDER: S-EPMC4927306 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature